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M94A2615.TXT
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1994-10-25
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Document 2615
DOCN M94A2615
TI AIDS and syphilis--an analysis of 129 HIV+ patients.
DT 9412
AU Pavan MH; Fornazieri ME; Abreu WB; Lima JN; Monteiro DT; Aoki FH; Inf.
Dis. Division-FMSc-St. Univ. of Campinas, SP, Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):264 (abstract no. PB0485). Unique
Identifier : AIDSLINE ICA10/94369960
AB OBJECTIVES: The main objective of this study is analyze the frequency of
syphilis in 129 HIV1 infected patients, the behaviour of non-treponemic
and treponemic testings and the spinal fluid analysis. METHODS: 129 HIV1
infected patients were studied retrospectively, followed at the
Ambulatory of HIV positive patients, from the Infectious Diseases
Division of this University. The main age were 29.61 (17-54) years old,
being 89(69%) from male sex and 40(31%) from female sex. The CDC
classification for these patients were: Group II-100(77.5%); Group
III-16(12.4%); Group IV-13(10.1%). The risk behaviour were:
IVDU-49(39.5%) Real contact with HIV+-21(16.3%); Homossexual-16(12.4%);
Promiscuous heterossexual-08(6.2%); Suspected contact with
HIV+-08(6.2%); Bissexual-07(5.4%); Bissex/IVDU-07(5.4%); Common
transfusion-04(3.1%); No risk group-04(3.1%); Promisc.
heterossex/IVDU-04(3.1%); Bissex/Common transf.-01(0.8%);
Heterossex/Common transf-01(0.8%). From 15 patients VDRL+, 7(46.7%) were
bissexuals, 5(33.3%) IVDU, 1(4.7%) infected by real contact, 1(4.7%) was
promiscuous heterossexual and 1(4.7%) was bissexual. Thus, 10 patients
were infected by sexual transmission and 5 by blood contamination.
RESULTS: From these 15 patients, 5 were not be investigated with spinal
fluid punction, for any reason. The other 10 patients were punctioned
with analysis of these fluids. From these 10 patients, 02(20%) had an
increasing on a white cell count and 1 of these 2, reagents for VDRL at
the spinal fluid. These 2 patients were treated with penicilin cristalin
and penicilin procain. Two others (20%) were treated with the same
scheme, one by maintence of headache and another by anexitis. Ten
patients from 15 were treated with usual dosis of penicilin benzatin and
1 were not trated, because the TPHA was not be reagent. After treatment
9 patients had an adequate response with treatment, according the CDC
parameters. 2 from 14 had treatment failure, being necessary a
retreatment. 3 of 14 patients have abandoned the Service. DISCUSSION AND
CONCLUSION: 1--The treatment with penicilin cristalin were satisfied in
this group of who had oportunity to be evaluated and had not signals or
simptoms, spinal fluid evaluation altered and compatible alterations
related to the neurosyphilis 2--10(66%) of the patients were infected by
and 5(33.3%) presumed by blood contact.
DE Acquired Immunodeficiency Syndrome/*DIAGNOSIS/DRUG THERAPY/
TRANSMISSION Adolescence Adult AIDS-Related Opportunistic
Infections/*DIAGNOSIS/DRUG THERAPY/ TRANSMISSION Bisexuality Blood
Transfusion Brazil Female Homosexuality Human HIV
Seropositivity/*DIAGNOSIS/DRUG THERAPY/TRANSMISSION *HIV-1 Male
Middle Age Penicillins/ADMINISTRATION & DOSAGE Risk Factors Syphilis
Serodiagnosis MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).